All rights reserved. Error if g! ReadFile path. Effects of a standardized extract of Ginkgo biloba, EGb , on the vascular endothelial growth factor-mediated angiogenesis in 3D-cultures. The beneficial effects of EGb are mainly ascribed to antioxidative, neuroprotective and vasoprotective properties.

However, the mechanisms of these effects are not yet well understood. In addition, EGb is known to contain terpenoids e. In this study, we investigated the potential of EGb to influence the VEGF-stimulated proliferation, migration and tube formation in an established 3D-model of vascular endothelial cells.

Pre-treatment with 2. In conclusion, we show for the first time that a standardized preparation of EGb, like its flavonoid constituents, inhibits the VEGF-mediated proliferation and migration in vascular endothelial cells. Therapeutic monoclonal antibodies mAbs have shown great promise in the therapy of different cancers. However, the typical half-life of therapeutic antibodies of. You must be logged in to post a comment.

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